Anti-KLF4 Antibody

Product Description

Specifications

Size	100 µL
Estimated Lead Time	1-2 weeks
Host Species	Mouse
Accession Number	O43474
Gene Id	9314
Gene Symbols	KLF4
Protein Name / Synonyms	Endothelial Kruppel like zinc finger protein;Epithelial zinc finger protein EZF;EZF;GKLF;Gut-enriched krueppel-like factor;KLF;KLF4;KLF4_HUMAN;Krueppel-like factor 4;Kruppel like factor 4 (Epithelial zinc finger protein EZF) (Gut enriched Krueppel like factor);Kruppel like factor 4 (gut).
Clonality	Monoclonal
Recommended Applications	Western Blotting
Research Area	Angiogenesis, Cancer, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Other Information

Antigen Type

Recombinant Protein

Images

WB (1:1000)

Western blot analysis of extracts from CHO-K1 cells, transfected with pcDNA3.1-Hygro(+)-mKLF4-Flag construct (A) or transfected with pDNA3.1-Hygro(+)-Flag vector (B),using KLF4 mouse mAb (1:1000 diluted).Predicted band size:55/65KDa.Observed band size:55/65KDa.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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