Rabbit Anti-Human LIG4 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P49917 |
| Gene Id | 3981 |
| Gene Symbols | LIG4 |
| Protein Name / Synonyms | LIG4 (N-term) |
| Clonality | Polyclonal |
| Preparation | This LIG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the N-terminal region of human LIG4. |
| Concentration (lot specific) | 0.400 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Specificity
Other Names
LIG4;DNA ligase 4; DNA ligase 4; DNA ligase IV; DNA ligase 4; Polydeoxyribonucleotide synthase [ATP] 4
NCBI Accession #
NP_001091738.1;NP_002303.2;NP_996820.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
103971
Recommended Dilutions
WB: 1:1000
 | LIG4 Antibody (N-term) (Cat# 102-14637) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the LIG4 antibody detected the LIG4 protein (arrow). |
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.