Anti-LINGO-1 (LRRN6A)-S596 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q9D1T0
Gene Id	235402
Gene Symbols	LINGO1
Protein Name / Synonyms	LINGO-1(LRRN6A)-S596 (C-term)
Clonality	Polyclonal
Preparation	This LINGO-1(LRRN6A) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-603 amino acids from the C-terminal region of human LINGO-1(LRRN6A).
Concentration (lot specific)	0.310 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

LINGO-1 is functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. LINGO-1 is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.

Specificity

Predicted Reactivity

Chicken, Monkey

Other Names

Lingo1; Lern1; Lrrn6a; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A

NCBI Accession #

NP_851419.1

Other Accession #

Q9N008; Q96FE5; Q50L44

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

69101

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	Western blot analysis of LINGO-1(LRRN6A)(Cat# 102-16408) in mouse liver tissue lysates (35ug/lane).LRRN6A (arrow) was detected using the purified Pab.
	LINGO-1(LRRN6A)-S596 (C-term) Antibody (Cat# 102-16408) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LINGO-1(LRRN6A)-S596 (C-term) Antibody for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

MOUSE

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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