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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q96FE5 |
| Gene Id | 84894 |
| Gene Symbols | LINGO1 |
| Protein Name / Synonyms | LINGO1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This LINGO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-92 amino acids from the N-terminal region of human LINGO1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
LINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.
Specificity
Predicted Reactivity
Mouse, Chicken, Monkey
Other Names
LINGO1; LERN1; LRRN6A; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; Leucine-rich repeat and immunoglobilin domain-containing protein 1; Leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A
NCBI Accession #
NP_116197.4
Other Accession #
Q9D1T0; Q9N008; Q50L44
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
69876
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Western blot analysis of LINGO1 (arrow) using rabbit polyclonal LINGO1 Antibody (N-term) (Cat# 102-17248).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LINGO1 gene (Lane 2) (Origene Technologies). |
 | Formalin-fixed and paraffin-embedded human brain tissue reacted with LINGO1 Antibody (N-term) (Cat# 102-17248), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.