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Anti-LMX1B (Center) Antibody
Catalog #: 102-18083
Rabbit Anti-LMX1B (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | O60663 |
| Gene Id | 4010 |
| Gene Symbols | LMX1B |
| Protein Name / Synonyms | LMX1B (Center) |
| Clonality | Polyclonal |
| Preparation | This LMX1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-202 amino acids from the Central region of human LMX1B. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
LMX1B is required for the normal development of the dopaminergic system. Loss of dopaminergic neurons is associated with one of the most prominent human neurological disorders, Parkinson's disease (PD). Dopaminergic neurons play an important role in the control of multiple brain functions including voluntary movement alongside an array of behavioral processes such as mood, reward, addiction, and stress. Lmx1b is one of several transcription factors involved in the generation of dopaminergic neurons in the brain.
Specificity
Predicted Reactivity
Chicken, Xenopus
Other Names
LMX1B; LIM homeobox transcription factor 1-beta; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B
NCBI Accession #
NP_001167618.1;NP_002307.2
Other Accession #
Q8UVR3; O88609; P53413
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
44917
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of LMX1B Antibody (Center) (Cat# 102-18083) in mouse heart tissue lysates (35ug/lane). LMX1B (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human testis tissue reacted with LMX1B Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Western blot analysis of LMX1B (arrow) using rabbit polyclonal LMX1B Antibody (Center) (Cat# 102-18083). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the LMX1B gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.