Anti-LRRC8A (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q8IWT6
Gene Id	56262
Gene Symbols	LRRC8A
Protein Name / Synonyms	LRRC8A(C-term)
Clonality	Polyclonal
Preparation	This LRRC8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 782-810 amino acids from the C-terminal region of human LRRC8A.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Specificity

Predicted Reactivity

Mouse, Rat

Other Names

LRRC8A; KIAA1437; LRRC8; Leucine-rich repeat-containing protein 8A

NCBI Accession #

NP_001120716.1;NP_001120717.1;NP_062540.2

Other Accession #

Q4V8I7; Q80WG5; NP_062540.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

94199

Recommended Dilutions

WB: 1:1000

LRRC8A Antibody (C-term) (Cat# 102-14307) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the LRRC8A antibody detected the LRRC8A protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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