Anti-LTB (C-term) (Ascites) Antibody

Product Description

Specifications

Size	0.1 mL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	Q06643
Gene Id	4050
Gene Symbols	LTB
Protein Name / Synonyms	LTB (C-term)(Ascites)
Clonality	Monoclonal
Preparation	This LTB antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 199-227 amino acids from the C-terminal region of human LTB.
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specificity

Predicted Reactivity

Pig

Other Names

LTB; TNFC; TNFSF3; Lymphotoxin-beta; Tumor necrosis factor C; Tumor necrosis factor ligand superfamily member 3

NCBI Accession #

NP_002332.1;NP_033666.1

Other Accession #

Q9TSV8; NP_033666.1; NP_002332.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

25390

Recommended Dilutions

WB: 1:2000-16000

LTB Antibody (C-term) (Cat# 102-10243) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the LTB antibody detected the LTB protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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