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Anti-LUM (Center) Antibody
Catalog #: 102-17450
Rabbit Anti-Human LUM (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P51884 |
| Gene Id | 4060 |
| Gene Symbols | LUM |
| Protein Name / Synonyms | LUM (Center) |
| Clonality | Polyclonal |
| Preparation | This LUM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the Central region of human LUM. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
Specificity
Predicted Reactivity
Mouse, Bovine
Other Names
LUM; LDC; SLRR2D; Lumican; Keratan sulfate proteoglycan lumican
NCBI Accession #
NP_002336.1
Other Accession #
P51885; Q05443
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
38429
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of LUM antibody (Center) (Cat# 102-17450) in A375 cell line lysates (35ug/lane). LUM (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with LUM Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | LUM Antibody (Center) (Cat# 102-17450) flow cytometric analysis of A375 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.