Anti-MAP2K1 (T291) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q02750
Gene Id	5604
Gene Symbols	MAP2K1
Protein Name / Synonyms	MAP2K1 (T291)
Clonality	Polyclonal
Preparation	This MAP2K1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-299 amino acids from human MAP2K1.
Concentration (lot specific)	0.320 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cardiovascular Disease, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

MAP2K1 is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Specificity

Predicted Reactivity

Mouse, Rat, Hamster, Rabbit

Other Names

MAP2K1; MEK1; PRKMK1; Dual specificity mitogen-activated protein kinase kinase 1; ERK activator kinase 1; MAPK/ERK kinase 1

NCBI Accession #

NP_002746.1

Other Accession #

Q01986; P29678; P31938; Q63980

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

43439

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	MAP2K1 Antibody (pT291) (Cat# 102-17727) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MAP2K1 antibody detected the MAP2K1 protein (arrow).
	Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with MAP2K1 Antibody (T291) (Cat# 102-17727), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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