Anti-MAP3K12 Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Accession Number	Q12852
Gene Id	7786
Gene Symbols	MAP3K12
Protein Name / Synonyms	MAP3K12
Clonality	Monoclonal
Preparation	This MAP3K12 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 828-859 amino acids from human MAP3K12.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq].

Specificity

Other Names

MAP3K12; ZPK; Mitogen-activated protein kinase kinase kinase 12; Dual leucine zipper bearing kinase; Leucine-zipper protein kinase; MAPK-upstream kinase; Mixed lineage kinase

NCBI Accession #

NP_001180440.1;NP_006292.3

Other Accession #

NP_001180440.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

93219

Recommended Dilutions

WB: 1:100-250

MAP3K12 Antibody (Cat# 102-10282) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the MAP3K12 antibody detected the MAP3K12 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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