Anti-MAPK11 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q15759
Gene Id	5600
Gene Symbols	MAPK11
Protein Name / Synonyms	MAPK11 (Center)
Clonality	Polyclonal
Preparation	This MAPK11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the Central region of human MAPK11.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	MAPK Signaling
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

P38 beta is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by changes in osmolarity of the extracellular environment, proinflammatory cytokines and cellular stress. This protein preferentially phosphorylates transcription factor ATF2. It is activated by phosphorylation on threonine and tyrosine by MKK6, and inhibited by pyridinyl-imidazole related compounds. Highest levels of expression are found in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.

Specificity

Other Names

MAPK11; PRKM11; SAPK2; SAPK2B; Mitogen-activated protein kinase 11; Mitogen-activated protein kinase p38 beta; Stress-activated protein kinase 2b; p38-2

NCBI Accession #

NP_002742.3

Other Accession #

Q9WUI1; Q2XNF2

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

41357

Recommended Dilutions

WB: 1:1000

	Western blot analysis of CTDSP1 (arrow) using rabbit polyclonal p38 beta Antibody (Center) (Cat# 102-17396). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CTDSP1 gene (Lane 2) (Origene Technologies).
	P38beta Antibody (Ctr) (Cat# 102-17396) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the P38beta antibody detected the P38beta protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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