Anti-MAPK14 (Y323) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	Q16539
Gene Id	1432
Gene Symbols	MAPK14
Protein Name / Synonyms	MAPK14 (Y323)
Clonality	Polyclonal
Preparation	This MAPK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-330 amino acids from human MAPK14.
Concentration (lot specific)	0.340 mg/ml
Recommended Applications	Western Blotting, FC
Research Area	Angiogenesis, Cancer, Inflammation, MAPK Signaling
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.

Specificity

Other Names

MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; Cytokine suppressive anti-inflammatory drug-binding protein; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; Stress-activated protein kinase 2a

NCBI Accession #

NP_001306.1;NP_620581.1;NP_620582.1;NP_620583.1

Other Accession #

P47811

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

41293

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	MAPK14 Antibody (Y322) (Cat# 102-17196) western blot analysis in Jurkat cell line and mouse kidney tissue lysates (35ug/lane).This demonstrates the MAPK14 antibody detected the MAPK14 protein (arrow).
	MAPK14 Antibody (Y323) (Cat# 102-17196) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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