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Anti-MARK4 (C-term) Antibody
Catalog #: 102-17150
Rabbit Anti-Human MARK4 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q96L34 |
| Gene Id | 57787 |
| Gene Symbols | MARK4 |
| Protein Name / Synonyms | MARK4 (C-term) |
| Clonality | Polyclonal |
| Preparation | This MARK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 611-641 amino acids from the C-terminal region of human MARK4. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
MARK4 contains an N-terminal serine/threonine kinase domain, a central ubiquitin-associated domain, and a C-terminal KA1-associated kinase domain. RT-PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells. Northern blot analysis reveals ubiquitous expression of a 3.6-kb transcript, with highest expression in testis. Immunofluorescence microscopy demonstrates homogeneous cytoplasmic expression. Colony-forming assays show that MARK4 antisense reduces the growth of SNU475 cells. It has been suggested that MARK4 provides a growth advantage to cells.
Specificity
Other Names
MARK4; KIAA1860; MARKL1; MAP/microtubule affinity-regulating kinase 4; MAP/microtubule affinity-regulating kinase-like 1
NCBI Accession #
NP_001186796.1;NP_113605.2
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
82520
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of anti-MARK4 Pab (Cat# 102-17150) in mouse liver tissue lysate (35ug/lane). MARK4(arrow) was detected using the purified Pab. |
 | Western blot analysis of MARK4 (arrow) using rabbit polyclonal hMARK4-R626 Antibody (Cat# 102-17150).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MARK4 gene (Lane 2) (Origene Technologies). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.