Anti-MCA1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q12904
Gene Id	9255
Gene Symbols	AIMP1
Protein Name / Synonyms	MCA1 (C-term)
Clonality	Polyclonal
Preparation	This MCA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-268 amino acids from the C-terminal region of human MCA1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Angiogenesis, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

MCA1 is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells.

Specificity

Predicted Reactivity

Mouse, Hamster

Other Names

AIMP1; EMAP2; SCYE1; Aminoacyl tRNA synthase complex-interacting multifunctional protein 1; Multisynthase complex auxiliary component p43; Endothelial monocyte-activating polypeptide 2; Endothelial monocyte-activating polypeptide II; Small inducible cytokine subfamily E member 1

NCBI Accession #

NP_001135887.1;NP_001135888.1;NP_004748.2

Other Accession #

P31230; O54873

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

34353

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	Western blot analysis of MCA1 antibody (C-term) (Cat# 102-16909) in 293 cell line lysates (35ug/lane). MCA1 (arrow) was detected using the purified Pab.
	Western blot analysis of MCA1(arrow) using rabbit polyclonal MCA1 Antibody (N-term) (Cat# 102-16909). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MCA1 gene (Lane 2) (Origene Technologies).
	MCA1 Antibody (C-term) (Cat# 102-16909) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymphnode followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MCA1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products