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Anti-MCF2L (C-term) Antibody

Catalog #: 102-23348

Rabbit Anti-MCF2L (C-term) Antibody, 400 µl

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
O15068|NP_001106203.1
Gene Id
23263
Gene Symbols
MCF2L
Protein Name / Synonyms
Guanine nucleotide exchange factor DBS, DBL's big sister, MCF2-transforming sequence-like protein, MCF2L, KIAA0362
ClonalityPolyclonal
CloneRB38890
IsotypeKappa, Rabbit
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.

Other Information

NCBI Accession #
NP_001106203.2;NP_079255.4
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
128109
Antigen Source
Human

Images

WB (1:1000)

MCF2L Antibody (C-term)(Cat. #102-23348) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MCF2L antibody detected the MCF2L protein (arrow).

WB

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.