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ISO 13485:2016 cGMP
Anti-MDM2 Antibody
Catalog #: DS-MB-01877
Mouse Anti-Human MDM2
Product Description
Specifications
| Size | 0.1 mg |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Specificity | This product recognizes the 90kD MDM2 protein, which forms a complex with p53 leading to p53 inhibition. MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. MDM2 is over expressed in a range of human malignancies, including soft tissue sarcomas, breast cancer and bladder cancer. |
| Host Species | Mouse |
| Protein Name / Synonyms | MDM2 |
| Concentration (lot specific) | IgG concentration 1.0 mg/ml |
| Recommended Applications | Immunohistology - Frozen, Immunoprecipitation, Immunohistology - Paraffin, Immunohistology - Resin |
| Research Area | Cancer, p53 Signaling, DNA Damage |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Storage/Stability
Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.
Format
Supplied as:
Purified IgG - liquid
Formulation:
Phosphate buffered saline
Format Type:
Purified
Preparation
Immunogen:
Synthetic peptide, CSRPSTSSRRRAISE, corresponding to amino acids 154-167 of human MDM2
Preservative:
0.09% Sodium Azide
This product
Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63Ag8.653 myeloma cell line.
Expiration:
12 months from the date of shipment when stored properly.