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Anti-MED14 (Center) Antibody
Catalog #: 102-11446
Rabbit Anti-Mouse MED14 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | O60244 |
| Gene Id | 9282 |
| Gene Symbols | MED14 |
| Protein Name / Synonyms | MED14 (Center) |
| Clonality | Polyclonal |
| Preparation | This MED14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-615 amino acids from the Central region of human MED14. |
| Concentration (lot specific) | 0.250 mg/ml |
| Recommended Applications | FC, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
Specificity
Other Names
MED14; ARC150; CRSP2; CXorf4; DRIP150; EXLM1; RGR1; TRAP170; Mediator of RNA polymerase II transcription subunit 14; Activator-recruited cofactor 150 kDa component; Cofactor required for Sp1 transcriptional activation subunit 2; Mediator complex subunit 14; RGR1 homolog; Thyroid hormone receptor-associated protein complex 170 kDa component; Transcriptional coactivator CRSP150; Vitamin D3 receptor-interacting protein complex 150 kDa component
NCBI Accession #
NP_004220.2
Other Accession #
NP_004220
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
160607
Recommended Dilutions
WB: 1:1000
 | MED14 Antibody (Center) (Cat# 102-11446) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the MED14 antibody detected the MED14 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.