Anti-MEF2C (S387) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q06413
Gene Id	4208
Gene Symbols	MEF2C
Protein Name / Synonyms	MEF2C (S387)
Clonality	Polyclonal
Preparation	This MEF2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-394 amino acids from human MEF2C.
Concentration (lot specific)	0.380 mg/ml
Recommended Applications	Western Blotting, IHC-P, IF
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. This protein controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It may also be involved in neurogenesis and in the development of cortical architecture.

Specificity

Predicted Reactivity

Pig

Other Names

MEF2C; Myocyte-specific enhancer factor 2C

NCBI Accession #

NP_001124477.1;NP_001180276.1;NP_001180277.1;NP_001180278.1;NP_001180279.1;NP_002388.2

Other Accession #

A4UTP7

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

51221

Recommended Dilutions

WB: 1:1000; IF: 1:10-50; IHC: 1:10-50

	MEF2C Antibody (pS387) (Cat# 102-16726) western blot analysis in HL-60,K562 cell line lysates (35ug/lane).This demonstrates the MEF2C antibody detected the MEF2C protein (arrow).
	Fluorescent confocal image of Hela cell stained with MEF2C Antibody (S387)(Cat# 102-16726).Hela cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with MEF2C primary antibody (1:25, 1 h at 37^°). For secondary antibody, Alexa Fluor^® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37^°).Cytoplasmic actin was counterstained with Alexa Fluor^® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37^°). Nuclei were counterstained with DAPI (blue) (10 µg/ml, 10 min).MEF2C immunoreactivity is localized to vesicles and Nucleus significantly.
	Formalin-fixed and paraffin-embedded human brain tissue reacted with MEF2C Antibody (S387) (Cat# 102-16726), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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