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Anti-Merlin (N-term) Antibody
Catalog #: 102-16936
Rabbit Anti-Human Merlin (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P35240 |
| Gene Id | 4771 |
| Gene Symbols | NF2 |
| Protein Name / Synonyms | Merlin (N-term) |
| Clonality | Polyclonal |
| Preparation | This Merlin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-95 amino acids from the N-terminal region of human Merlin. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, IF |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Merlin is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This protein has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
NF2; SCH; Merlin; Moesin-ezrin-radixin-like protein; Neurofibromin-2; Schwannomerlin; Schwannomin
NCBI Accession #
NP_000259.1;NP_057502.2;NP_861546.1;NP_861966.1;NP_861967.1;NP_861968.1;NP_861969.1;NP_861970.1;NP_861971.1
Other Accession #
Q63648; P46662
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
69690
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; IF: 1:10-50
 | Western blot analysis of Merlin Antibody (N-term) (Cat# 102-16936) in NCI-H460 cell line lysates (35ug/lane). NF2 (arrow) was detected using the purified Pab. |
 | Merlin Antibody (N-term) (Cat# 102-16936) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the Merlin Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | Confocal immunofluorescent analysis of Merlin Antibody (N-term)(Cat# 102-16936) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.