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Anti-METAP2 (N-term) Antibody
Catalog #: 102-12468
Rabbit Anti-Human METAP2 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P50579 |
| Gene Id | 10988 |
| Gene Symbols | METAP2 |
| Protein Name / Synonyms | METAP2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This METAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human METAP2. |
| Concentration (lot specific) | 0.490 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2.
Specificity
Other Names
METAP2; MNPEP; P67EIF2; Methionine aminopeptidase 2; Initiation factor 2-associated 67 kDa glycoprotein; Peptidase M 2; p67eIF2
NCBI Accession #
NP_006829.1
Other Accession #
NP_006829.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
52892
Recommended Dilutions
WB: 1:1000
 | METAP2 Antibody (N-term) (Cat# 102-12468) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the METAP2 antibody detected the METAP2 protein (arrow). |
 | Western blot analysis of METAP2 (arrow) using rabbit polyclonal METAP2 Antibody (N-term) (Cat# 102-12468). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the METAP2 gene. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.