3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-MFN2 (Center) Antibody
Catalog #: 102-18050
Rabbit Anti-Human MFN2 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O95140 |
| Gene Id | 9927 |
| Gene Symbols | MFN2 |
| Protein Name / Synonyms | MFN2 (Center) |
| Clonality | Polyclonal |
| Preparation | This MFN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 447-476 amino acids from the Central region of human MFN2. |
| Concentration (lot specific) | 0.440 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
MFN2; CPRP1; KIAA0214; Mitofusin-2; Transmembrane GTPase MFN2
NCBI Accession #
NP_001121132.1;NP_055689.1
Other Accession #
Q8R500; Q80U63
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
86402
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of MFN2 Antibody (Center) (Cat# 102-18050) in K562 cell line lysates (35ug/lane). MFN2 (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded mouse kidney reacted with MFN2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | MFN2 Antibody (Center)(Cat# 102-18050) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.