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Anti-MLH1 (Center) Antibody
Catalog #: 102-11205
Rabbit Anti-Human MLH1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P40692 |
| Gene Id | 4292 |
| Gene Symbols | MLH1 |
| Protein Name / Synonyms | MLH1 (Center) |
| Clonality | Polyclonal |
| Preparation | This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the Central region of human MLH1. |
| Concentration (lot specific) | 0.400 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Specificity
Other Names
MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
NCBI Accession #
NP_000240.1;NP_001161089.1;NP_001161090.1;NP_001161091.1;NP_001245200.1;NP_001245202.1;NP_001245203.1
Other Accession #
NP_001161090.1; NP_001161091.1; NP_000240.1; NP_001161089.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
84601
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | MLH1 Antibody (Center) (Cat# 102-11205) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MLH1 antibody detected the MLH1 protein (arrow). |
 | MLH1 Antibody (Center) (Cat# 102-11205) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.