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Anti-MLL3 Antibody
Catalog #: 102-20221
Mouse Anti-MLL3 Antibody, 200 µl
Product Description
Specifications
| Size | 200 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Mouse |
| Accession Number | Q8NEZ4 |
| Gene Id | 58508 |
| Gene Symbols | KMT2C |
| Protein Name / Synonyms | Histone-lysine N-methyltransferase 2C, Lysine N-methyltransferase 2C, 2.1.1.43, Homologous to ALR protein, Myeloid/lymphoid or mixed-lineage leukemia protein 3, KMT2C, HALR, KIAA1506, MLL3 |
| Clonality | Monoclonal |
| Clone | 1686CT202.60.69 |
| Isotype | Kappa, IgG1 |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
Other Information
Antigen Type
Recombinant Protein
Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Calculated Molecular Weight (Da)
541370
Antigen Source
Human
Images
WB (1:2000)
Anti-MLL3 Antibody at 1:2000 dilution + Recombinant protein at 20 ng per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 541 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.