Anti-MLLT7 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P98177
Gene Id	4303
Gene Symbols	FOXO4
Protein Name / Synonyms	MLLT7 (N-term)
Clonality	Polyclonal
Preparation	This MLLT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human MLLT7.
Concentration (lot specific)	0.400 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Angiogenesis
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The MLLT7 (Mixed-lineage leukemia translocated to 7) protein is a forkhead transcription factor that activates apoptosis by inducing the BCL-6 transcriptional repressor. MLL-MLLT7 fusion protein transformw myeloid progenitors and impairs forkhead protein function. MLLT7 is a target of the phosphatidylinositol 3-kinase/PKB insulin signaling pathway and the AMP-activated protein kinase-dependent pathway.

Specificity

Other Names

FOXO4; AFX; AFX1; MLLT7; Forkhead box protein O4; Fork head domain transcription factor AFX1

NCBI Accession #

NP_001164402.1;NP_005929.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

53684

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	MLLT7 Antibody (R59) (Cat# 102-16672) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MLLT7 antibody detected the MLLT7 protein (arrow).
	MLLT7 antibody (N-term) (Cat# 102-16672)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MLLT7 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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