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Anti-MMP2 (Ascites) Antibody
Catalog #: 102-10068
Mouse Anti-Human MMP2 (Ascites) Antibody, 0.1 ml
Product Description
Specifications
| Size | 0.1 mL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | P08253 |
| Gene Id | 4313 |
| Gene Symbols | MMP2 |
| Protein Name / Synonyms | MMP2 (Ascites) |
| Clonality | Monoclonal |
| Preparation | This MMP2 antibody is generated from mouse immunized with MMP2 recombinant protein. |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Angiogenesis, Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Specificity
Other Names
MMP2; CLG4A; 72 kDa type IV collagenase; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; TBE-1; PEX
NCBI Accession #
NP_001121363.1;NP_004521.1
Format
Type
Purified Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
73882
Recommended Dilutions
WB: 1:200-1000; IHC: 1:50-100
 | Western blot analysis of MMP2 Antibody (Cat# 102-10068) in T47D cell line lysates (35ug/lane).MMP2 (arrow) was detected using the purified Mab.(1:200) |
 | MMP2 antibody (Cat# 102-10068) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MMP2 antibody for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.