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Anti-Mouse Abl1 (Center) Antibody
Catalog #: 102-12215
Rabbit Anti-Mouse Abl1 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | P00520 |
| Gene Id | 11350 |
| Gene Symbols | ABL1 |
| Protein Name / Synonyms | Abl1 (Center) |
| Clonality | Polyclonal |
| Preparation | This Mouse Abl1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the Central region of mouse Abl1. |
| Concentration (lot specific) | 0.430 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Angiogenesis, Cardiovascular Disease, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
Specificity
Other Names
Abl1; Abl; Tyrosine-protein kinase ABL1; Abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Proto-oncogene c-Abl; p150
NCBI Accession #
NP_001106174.1;NP_033724.2
Other Accession #
NP_033724.2; NP_001106174.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
122673
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | Mouse Abl1 Antibody (Center) (Cat# 102-12215) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the Abl1 antibody detected the Abl1 protein (arrow). |
 | Mouse Abl1 Antibody (Center) (102-12215)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse duodenum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Abl1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
MOUSE
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.