Anti-Mouse beta-Glucan Receptor Antibody

Catalog #: DS-MB-03704

Rat Anti-Mouse beta-Glucan Receptor

Product Description

Specifications

Size	0.5 mg
Estimated Lead Time	1-2 weeks
Species	Mouse
Specificity	This product recognizes murine beta-glucan receptor, also known as Dectin-1.Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk.
Protein Name / Synonyms	beta-Glucan Receptor
Concentration (lot specific)	IgG concentration 1.0 mg/ml
Recommended Applications	Immunohistology - Frozen, Flow Cytometry, Functional Assays, Immunoprecipitation
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Storage/Stability

Store at -20 °C only.

This product should be stored undiluted.

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG - liquid

Formulation:

Phosphate buffered saline

Quality Control (Contaminants):

<0.01 EU/ug

Format Type:

Low Endotoxin

Preparation

Immunogen:

Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Preservative:

None present

This product

Spleen cells from immunised Fischer rats were fused with cells of the rat Y3 myeloma cell line

Expiration:

12 months from the date of shipment when stored properly.

Featured Products