Anti-Mouse beta-Glucan Receptor Antibody, RPE

Catalog #: DS-MB-03705

Rat Anti-Mouse beta-Glucan Receptor [+RPE]

Product Description

Specifications

Size	100 tests
Estimated Lead Time	1-2 weeks
Species	Mouse
Specificity	This product recognizes murine beta-glucan receptor, also known as Dectin-1.Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. As a major leucocyte receptor for beta-glucan this molecule may have a key role in the immunomodulatory effects of beta-glucans and in the host response to fungal pathogens. Recent work has shown that Dectin-1 may stimulate reactive oxygen production in macropahges via the protein tyrosine kinase known as Syk.
Protein Name / Synonyms	beta-Glucan Receptor
Recommended Applications	Flow Cytometry
Reconstitution	Reconstitute with 1 ml distilled water
Research Area	Cardiovascular Disease
Shipping Type	Ambient temperature
Storage	4°C

Description

Storage/Stability

Store at +4 °C.

DO NOT FREEZE

This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgG conjugated to R. Phycoerythrin (RPE) - lyophilized

Formulation:

Phosphate buffered saline

Reconstitution:

Reconstitute with 1 ml distilled water

Preparation

Immunogen:

Dectin-1 transfected NIH3T3 cells and recombinant soluble Dectin-1

Preservative:

0.09%	Sodium Azide
1%	Bovine Serum Albumin
5%	Sucrose

This product

Spleen cells from immunised Fischer rats were fused with cells of the rat Y3 myeloma cell line

Expiration:

12 months from the date of shipment when stored properly.

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