Rabbit Anti-Mouse Bmp1 (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | P13497 |
| Gene Id | 649 |
| Gene Symbols | BMP1 |
| Protein Name / Synonyms | Bmp1 (C-term) |
| Clonality | Polyclonal |
| Preparation | This Bmp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-986 amino acids from the C-terminal region of human Bmp1. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | IHC-P, Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.
Specificity
Other Names
BMP1; PCOLC; Bone morphogenetic protein 1; Mammalian tolloid protein; Procollagen C-proteinase
NCBI Accession #
NP_001190.1;NP_006120.1
Other Accession #
P98063
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
111249
Recommended Dilutions
IHC: 1:50-100; WB: 1:1000
 | Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
 | Bmp1 Antibody (R972) (Cat# 102-13290) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Bmp1 antibody detected the Bmp1 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.