Anti-Mouse Cbx5 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Mouse
Host Species	Rabbit
Accession Number	Q61686
Gene Id	12419
Gene Symbols	CBX5
Protein Name / Synonyms	Cbx5 (C-term)
Clonality	Polyclonal
Preparation	This Mouse Cbx5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-186 amino acids from the C-terminal region of mouse Cbx5.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins (By similarity).

Specificity

Predicted Reactivity

Human

Other Names

Cbx5; Hp1a; Chromobox protein homolog 5; Heterochromatin protein 1 homolog alpha

NCBI Accession #

NP_001070257.1;NP_001103686.1;NP_031652.1

Other Accession #

P45973; NP_001070257.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

22186

Recommended Dilutions

WB: 1:1000

Mouse Cbx5 Antibody (C-term) (Cat# 102-14193) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the Cbx5 antibody detected the Cbx5 protein (arrow).

Antigen Source

MOUSE

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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