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Anti-Mouse Cdc25A (N-term) Antibody
Catalog #: 102-16714
Rabbit Anti-Human Cdc25A (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P30304 |
| Gene Id | 993 |
| Gene Symbols | CDC25A |
| Protein Name / Synonyms | Cdc25A (N-term) |
| Clonality | Polyclonal |
| Preparation | This Cdc25A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Cdc25A. |
| Concentration (lot specific) | 0.320 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.
Specificity
Other Names
CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A
NCBI Accession #
NP_001780.2;NP_963861.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
59087
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of Cdc25A Pab (Cat# 102-16714) in mouse kidney tissue lysates (35ug/lane). Cdc25A (arrow) was detected using the purified Pab. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.