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Anti-Mouse EIF3C (Center) Antibody
Catalog #: 102-12961
Rabbit Anti-Mouse EIF3C (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | Q99613 |
| Gene Id | 8663 |
| Gene Symbols | EIF3C |
| Protein Name / Synonyms | EIF3C (Center) |
| Clonality | Polyclonal |
| Preparation | This EIF3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 538-566 amino acids from the Central region of human EIF3C. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Specificity
Predicted Reactivity
Human, Rat, Bovine, Xenopus
Other Names
EIF3C; EIF3S8; Eukaryotic translation initiation factor 3 subunit C; Eukaryotic translation initiation factor 3 subunit 8; eIF3 p110
NCBI Accession #
NP_001032897.1;NP_001186071.1;NP_001254503.1;NP_003743.1
Other Accession #
B5ME19; Q4QR58; B5DFC8; Q8R1B4; Q3SYW6; NP_001032897.1; NP_003743.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
105344
Recommended Dilutions
WB: 1:1000
 | EIF3C Antibody (Center) (Cat# 102-12961) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the EIF3C antibody detected the EIF3C protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.