This product recognizes the mouse Gr-1 antigen, a 21❏❏25kD cell surface protein that belongs to the Ly-6 family of proteins. This antibody reacts predominantly with the Ly-6G protein but weaker reactivity with the Ly-6C protein has been demonstrated.

The Gr-1 antigen is primarily a marker of myeloid differentiation. In the bone marrow the level of Gr-1 expression is low on immature myeloblasts and increases as the myeloid cells mature to granulocytes. Gr-1 is also expressed on macrophages and transiently on differentiating monocytes.

IgG concentration 1.0 mg/ml