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Anti-Mouse Krt6a (Center) Antibody

Catalog #: 102-14381

Rabbit Anti-Mouse Krt6a(Center) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesMouse
Host SpeciesRabbit
Accession Number
P50446
Gene Id
16687
Gene Symbols
KRT6A
Protein Name / Synonyms
Krt6a(Center)
ClonalityPolyclonal
PreparationThis Mouse Krt6a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of mouse Krt6a.
Concentration (lot specific)
0.440 mg/ml
Recommended ApplicationsWestern Blotting
Research AreaCardiovascular Disease
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. There are at least six isoforms of human type II keratin 6 (K6), K6A being the most abundant representing about 77% of all forms found in epithelia.

Specificity

Other Names
Krt6a; Ker2; Krt2-6; Krt2-6a; Krt6; Keratin, type II cytoskeletal 6A; Cytokeratin-6A; Keratin-6-alpha; Keratin-6A
NCBI Accession #
NP_032502.3
Other Accession #
Q9Z331; NP_032502.3

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
59335
Recommended Dilutions
WB: 1:1000
Mouse Krt6a Antibody (Center) (Cat# 102-14381) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the Mouse Krt6a antibody detected the Mouse Krt6a protein (arrow).

Antigen Source

MOUSE

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.