Anti-Mouse PDE8B (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Mouse
Host Species	Rabbit
Accession Number	O95263
Gene Id	8622
Gene Symbols	PDE8B
Protein Name / Synonyms	PDE8B (Center)
Clonality	Polyclonal
Preparation	This PDE8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the Central region of human PDE8B.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.

Specificity

Other Names

PDE8B; High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; Cell proliferation-inducing gene 22 protein

NCBI Accession #

NP_001025022.1;NP_001025023.1;NP_001025024.1;NP_001025025.1;NP_003710.1

Other Accession #

E9Q4S1; NP_003710.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

98979

Recommended Dilutions

WB: 1:1000

PDE8B Antibody (Center) (Cat# 102-14518) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PDE8B antibody detected the PDE8B protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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