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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | Q61337 |
| Gene Id | 12015 |
| Gene Symbols | BAD |
| Protein Name / Synonyms | Phospho-BAD(S112) |
| Clonality | Polyclonal |
| Preparation | This mouse BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S112 of mouse BAD. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Dot Blotting |
| Research Area | Apoptosis, Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
BAD promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Specificity
Predicted Reactivity
Rat
Other Names
Bad; Bbc6; Bcl2 antagonist of cell death; Bcl-2-binding component 6; Bcl-xL/Bcl-2-associated death promoter
NCBI Accession #
NP_031548.1
Other Accession #
O35147; NP_031548.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
22080
Recommended Dilutions
DB: 1:500
 | Dot blot analysis of Phospho-mouse BAD-S112 Antibody Phospho-specific Pab (Cat# 102-15567) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. |
Antigen Source
MOUSE
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.