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Anti-Mouse Phospho-mouse FADD (S191) Antibody
Catalog #: 102-15299
Rabbit Anti-Mouse Phospho-mouse FADD(S191) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | Q61160 |
| Gene Id | 14082 |
| Gene Symbols | FADD |
| Protein Name / Synonyms | Phospho-FADD(S191) |
| Clonality | Polyclonal |
| Preparation | This mouse FADD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S191 of mouse FADD. |
| Concentration (lot specific) | 0.330 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Apoptosis, Cardiovascular Disease, Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
FADD is an apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Specificity
Other Names
Fadd; Mort1; Protein FADD; FAS-associated death domain protein; FAS-associating death domain-containing protein; Mediator of receptor induced toxicity
NCBI Accession #
NP_034305.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
22960
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of anti-mFADD Pab (Cat# 102-15299) in mouse heart tissue lysate.mFADD(arrow) was detected using the purified Pab. |
Antigen Source
MOUSE
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.