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Anti-Mouse Phospho-mouse p21Cip1 (S78) Antibody
Catalog #: 102-15724
Rabbit Anti-Mouse Phospho-mouse p21Cip1(S78) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | P39689 |
| Gene Id | 12575 |
| Gene Symbols | CDKN1A |
| Protein Name / Synonyms | Phospho-p21Cip1(S78) |
| Clonality | Polyclonal |
| Preparation | This mouse p21Cip1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S78 of mouse p21Cip1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Dot Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.
Specificity
Other Names
Cdkn1a; Cip1; Waf1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; Melanoma differentiation-associated protein; p21
NCBI Accession #
NP_001104569.1;NP_031695.1
Other Accession #
NP_001129489.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
17785
Recommended Dilutions
DB: 1:500
 | Dot blot analysis of Mouse p21Cip1 Antibody (Phospho S78) Phospho-specific Pab (Cat# 102-15724) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. |
Antigen Source
MOUSE
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.