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Anti-Mouse POF1B (Center) Antibody
Catalog #: 102-12183
Rabbit Anti-Mouse POF1B (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Mouse |
| Host Species | Rabbit |
| Accession Number | Q8WVV4 |
| Gene Id | 79983 |
| Gene Symbols | POF1B |
| Protein Name / Synonyms | POF1B (Center) |
| Clonality | Polyclonal |
| Preparation | This POF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the Central region of human POF1B. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called 'POF1' and 'POF2' have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined.
Specificity
Other Names
POF1B; Protein POF1B; Premature ovarian failure protein 1B
NCBI Accession #
NP_079197.3
Other Accession #
NP_079197.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
68065
Recommended Dilutions
WB: 1:1000
 | POF1B Antibody (Center) (Cat# 102-12183) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the POF1B antibody detected the POF1B protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.