Anti-Mouse PPARA (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Mouse
Host Species	Rabbit
Accession Number	Q07869
Gene Id	5465
Gene Symbols	PPARA
Protein Name / Synonyms	PPARA (Center)
Clonality	Polyclonal
Preparation	This PPARA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-181 amino acids from the Central region of human PPARA.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, FC
Research Area	Cardiovascular Disease, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

Specificity

Predicted Reactivity

Rat, Xenopus

Other Names

PPARA; NR1C1; PPAR; Peroxisome proliferator-activated receptor alpha; Nuclear receptor subfamily 1 group C member 1

NCBI Accession #

NP_001001928.1;NP_005027.2

Other Accession #

P37232; P37230; P23204; NP_005027.2; NP_001001928.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

52225

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	PPARA Antibody (Center) (Cat# 102-11787) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PPARA antibody detected the PPARA protein (arrow).
	PPARA Antibody (Center) (Cat# 102-11787) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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