Anti-Mouse S100B Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Mouse
Accession Number	P04271
Gene Id	6285
Gene Symbols	S100B
Protein Name / Synonyms	S100B
Clonality	Monoclonal
Preparation	This S100B monoclonal antibody is generated from mouse immunized with S100B recombinant protein.
Concentration (lot specific)	1.400 mg/ml
Recommended Applications	Western Blotting
Research Area	Neuroscience, Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Specificity

Predicted Reactivity

Rabbit

Other Names

S100B; Protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B

NCBI Accession #

NP_006263.1

Other Accession #

Q6YNR6; NP_006263.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

10713

Recommended Dilutions

WB: 1:100-250

S100B Antibody (Cat# 102-10173) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the S100B antibody detected the S100B protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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