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Anti-Mouse SHANK2 (Center) Antibody

Catalog #: 102-11731

Rabbit Anti-Mouse SHANK2 (Center) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesMouse
Host SpeciesRabbit
Accession Number
Q9UPX8
Gene Id
22941
Gene Symbols
SHANK2
Protein Name / Synonyms
SHANK2 (Center)
ClonalityPolyclonal
PreparationThis SHANK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 879-908 amino acids from the Central region of human SHANK2.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting
Research AreaCardiovascular Disease
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq].

Specificity

Other Names
SHANK2; CORTBP1; KIAA1022; PROSAP1; SH3 and multiple ankyrin repeat domains protein 2; Cortactin-binding protein 1; Proline-rich synapse-associated protein 1
NCBI Accession #
NP_036441.2
Other Accession #
Q80Z38; NP_036441.2

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
158822
Recommended Dilutions
WB: 1:1000
SHANK2 Antibody (Center) (Cat# 102-11731) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the SHANK2 antibody detected the SHANK2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.