Anti-Mouse STC2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Mouse
Host Species	Rabbit
Accession Number	O76061
Gene Id	8614
Gene Symbols	STC2
Protein Name / Synonyms	STC2 (C-term)
Clonality	Polyclonal
Preparation	This STC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-302 amino acids from the C-terminal region of human STC2.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.

Specificity

Predicted Reactivity

Rat

Other Names

STC2; Stanniocalcin-2; Stanniocalcin-related protein

NCBI Accession #

NP_003705.1

Other Accession #

Q9R0K8; O88452; NP_003705.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

33249

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	STC2 Antibody (C-term) (Cat# 102-12425) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the STC2 antibody detected the STC2 protein (arrow).
	STC2 Antibody (C-term) (Cat# 102-12425)immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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