Anti-MRGBP (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9NV56
Gene Id	55257
Gene Symbols	MRGBP
Protein Name / Synonyms	MRGBP (Center)
Clonality	Polyclonal
Preparation	This MRGBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the Central region of human MRGBP.
Concentration (lot specific)	0.480 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Specificity

Predicted Reactivity

Mouse

Other Names

MRGBP; C20orf20; MRG-binding protein

NCBI Accession #

NP_060740.1

Other Accession #

Q9DAT2; NP_060740.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

22417

Recommended Dilutions

WB: 1:1000

MRGBP Antibody (Center) (Cat# 102-13667) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MRGBP antibody detected the MRGBP protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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