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Anti-MRGPRX2 (C-term) Antibody
Catalog #: 102-22339
Rabbit Anti-MRGPRX2 (C-term) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q96LB1|NP_473371.1 |
| Gene Id | 117194 |
| Gene Symbols | MRGPRX2 |
| Protein Name / Synonyms | Mas-related G-protein coupled receptor member X2, MRGPRX2, MRGX2 |
| Clonality | Polyclonal |
| Clone | RB36019 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
MRGPRX2 is the orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
Other Information
NCBI Accession #
NP_473371.1
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Calculated Molecular Weight (Da)
37099
Antigen Source
Human
Images
WB (1:1000)
MRGPRX2 Antibody (C-term) (Cat. #102-22339) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MRGPRX2 antibody detected the MRGPRX2 protein (arrow).
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.