Anti-MRPL11 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9Y3B7
Gene Id	65003
Gene Symbols	MRPL11
Protein Name / Synonyms	MRPL11 (N-term)
Clonality	Polyclonal
Preparation	This MRPL11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-62 amino acids from the N-terminal region of human MRPL11.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q.

Specificity

Other Names

MRPL11; 39S ribosomal protein L11, mitochondrial

NCBI Accession #

NP_057134.1;NP_733934.1;NP_733935.1

Other Accession #

NP_057134.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

20683

Recommended Dilutions

WB: 1:1000

MRPL11 Antibody (N-term) (Cat# 102-14159) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the MRPL11 antibody detected the MRPL11 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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