Anti-MRPL40 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9NQ50
Gene Id	64976
Gene Symbols	MRPL40
Protein Name / Synonyms	MRPL40 (C-term)
Clonality	Polyclonal
Preparation	This MRPL40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the C-terminal region of human MRPL40.
Concentration (lot specific)	0.430 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.

Specificity

Other Names

MRPL40; NLVCF; URIM; 39S ribosomal protein L40, mitochondrial; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Up-regulated in metastasis

NCBI Accession #

NP_003767.2

Other Accession #

NP_003767.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

24490

Recommended Dilutions

WB: 1:1000

MRPL40 Antibody (C-term) (Cat# 102-13943) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the MRPL40 antibody detected the MRPL40 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products