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Anti-MSH-alpha Antibody, Biotinylated
Catalog #: RB-13-0008B-50
Rabbit anti-MSH-alpha Biotinylated Antibody, 50 ug
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P01189 |
| Gene Id | 5443 |
| Gene Symbols | POMC |
| Clonality | Polyclonal |
| Immunogen | Immunogen was synthetic peptide derived from human MSH-alpha. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum followed by Protein A/G affinity chromatography. |
| Immunogen Sequence | CSYSMEHFRWGKPVGKKR |
| Isotype | IgG |
| Recommended Applications | ELISA (recommended work dilution= 1 : 16, 000) |
| Reconstitution | A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e.g. sodium azide). The final amount is indicated on the shipping vial. |
| Research Area | Cancer |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Expiration
12 months from the date of shipment when stored properly.
Description
The melanocyte-stimulating hormones (MSH) are a class of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland. MSH belongs to a group called the melanocortins. This group includes ACTH, alpha-melanocyte-stimulating hormone (alpha-MSH), beta-melanocyte-stimulating hormone (beta-MSH) and gamma-melanocyte-stimulating hormone (?-MSH); these peptides are all cleavage products of a large precursor peptide called pro-opiomelanocortin (POMC). alpha-MSH is the most important melanocortin for pigmentation.
Storage / Stability
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Specificity
The antibody can specifically bind to human MSH-alpha. No cross reactivity was observed with unrelated antigens in ELISA. The specificity for binding to recombinant protein, cellular protein and native antigen is not defined. Cross reactivity with mouse or rat MSH-alpha was not tested.
References
- Hadley ME (Oct 2005). "Discovery that a melanocortin regulates sexual functions in male and female humans". Peptides 26 (10): 16879. Millington GW (May 2006). "Proopiomelanocortin (POMC): the cutaneous roles of its melanocortin products and receptors". Clin. Exp. Dermatol. 31 (3): 40712
- Millington GW (2007). "The role of proopiomelanocortin (POMC) neurones in feeding behaviour". Nutr Metab (Lond) 4: 18.