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Anti-MSH2 (Center) Antibody
Catalog #: 102-11154
Rabbit Anti-Human MSH2 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P43246 |
| Gene Id | 4436 |
| Gene Symbols | MSH2 |
| Protein Name / Synonyms | MSH2 (Center) |
| Clonality | Polyclonal |
| Preparation | This MSH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-665 amino acids from the Central region of human MSH2. |
| Concentration (lot specific) | 0.250 mg/ml |
| Recommended Applications | Western Blotting, IF, FC |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq].
Specificity
Other Names
MSH2; DNA mismatch repair protein Msh2; MutS protein homolog 2
NCBI Accession #
NP_000242.1;NP_001245210.1
Other Accession #
NP_000242.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
104743
Recommended Dilutions
WB: 1:1000; IF: 1:10-50; FC: 1:10-50
 | MSH2 Antibody (Center) (Cat# 102-11154) western blot analysis in SW480,U251 cell line lysates (35ug/lane).This demonstrates the MSH2 antibody detected the MSH2 protein (arrow). |
 | Confocal immunofluorescent analysis of MSH2 Antibody (Center)(Cat# 102-11154) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). |
 | MSH2 Antibody (Center) (Cat# 102-11154) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.