Anti-Msx2 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P35548
Gene Id	4488
Gene Symbols	MSX2
Protein Name / Synonyms	Msx2 (C-term)
Clonality	Polyclonal
Preparation	This Msx2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-222 amino acids from the C-terminal region of human Msx2.
Concentration (lot specific)	0.390 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Cardiovascular Disease
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.

Specificity

Other Names

Homeobox protein MSX-2; Hox-8; MSX2; HOX8

NCBI Accession #

NP_002440.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

28897

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	Western blot analysis of Msx2 (arrow) using rabbit polyclonal Msx2 Antibody (Human C-term) (Cat# 102-15073). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Msx2 gene (Lane 2) (Origene Technologies).
	Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Msx2 Antibody (C-term) (Cat# 102-15073), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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